Available Vaccinations
There are two vaccines available to prevent mpox and other orthopox viruses:
- JYNNEOS, a replication-deficient live Vaccinia virus vaccine, licensed in 2019, and
- ACAM2000, a replication-competent live Vaccinia virus vaccine.
Due to the safety profile of the two vaccines, JYNNEOS is preferred over ACAM2000 for mpox prevention. Persons at risk for occupational exposure to mpox will be offered vaccination.